Preheat your oven to 375 degrees Fahrenheit (190 degrees Celsius).
Take a 9x13-inch baking dish and lightly coat it with nonstick spray to prevent sticking.
Use a flat meat pounder or rolling pin to gently pound the chicken breasts until they reach an even thickness.
Mix together the sour cream, garlic powder, paprika, and onion powder in a shallow dish until thoroughly combined.
Take a second shallow dish and add the Ritz crackers to it.
Start by dipping each piece of chicken into the sour cream mixture, then coat it thoroughly with the cracker crumbs, pressing down to ensure the crumbs stick to the chicken.
Transfer the chicken to the prepared baking dish and pour the melted butter over the top, ensuring all pieces are evenly coated.
Allow the chicken to bake in the oven for approximately 30 minutes.
Checking for doneness by using a meat thermometer to ensure it reaches 165 degrees Fahrenheit.
After baking, allow the chicken to rest for a few minutes before slicing and serving.